Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sequence-specific DNA Binding Activity of RNA Helicase A to the p16 Promoter

1 Jan 2001

Abstract excerpt

p16(INK4a) is frequently altered in human cancer, often through epigenetically mediated transcriptional silencing. However, little is known about the transcriptional regulation of this gene. To learn more about such control, we initiated studies of proteins that bind to the promoter in cancer cells that do, and do not, express the gene. We identify RNA helicase A (RHA) as a protein that binds much better to the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to Epigenetics and DNA Methylation
Share to Genomics and Chromatin Dynamics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 11038348
DOI: 10.1074/jbc.m004481200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sequence-specific DNA Binding Activity of RNA Helicase A to the p16 PromoterPMID 11038348Read ↗

BRCA1, histone H2AX phosphorylation, and male meiotic sex chromosome inactivation.Semantic proximity Read ↗

Werner syndrome RECQ helicase participates in and directs maintenance of the protein complexes of constitutive heterochromatin in proliferating human cellsSemantic proximity Read ↗

Sp1-mediated transcription of the Werner helicase gene is modulated by Rb and p53.Semantic proximity Read ↗

Modulation of Heterochromatin by Male Specific Lethal Proteins and roX RNA in Drosophila melanogaster Males.Semantic proximity Read ↗

Long noncoding RNA, polycomb, and the ghosts haunting INK4b-ARF-INK4a expression.Semantic proximity Read ↗

Expression of DNA Methyltransferase 1 Is Activated by Hepatitis B Virus X Protein via a Regulatory Circuit Involving the p16INK4a-Cyclin D1-CDK 4/6-pRb-E2F1 PathwaySemantic proximity Read ↗

Structure-function analysis of the RNA helicase maleless.Semantic proximity Read ↗

RNA helicase A in the MEF1 transcription factor complex up-regulates the MDR1 gene in multidrug-resistant cancer cells.Semantic proximity Read ↗

Senescence delay and repression of p16 INK4a by Lsh via recruitment of histone deacetylases in human diploid fibroblastsSemantic proximity Read ↗

<i>INK4</i> locus of the tumor-resistant rodent, the naked mole rat, expresses a functional p15/p16 hybrid isoformSemantic proximity Read ↗

Drosophila MSL complex globally acetylates H4K16 on the male X chromosome for dosage compensation.Semantic proximity Read ↗

ATM pathway activation limits R-loop-associated genomic instability in Werner syndrome cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.