Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The TBP-like factor CeTLF is required to activate RNA polymerase II transcription during C. elegans embryogenesis.

Molecular cell - 1 Sept 2000

Kaltenbach L, Horner M A, Rothman J H, Mango S E

Abstract excerpt

Metazoans possess two TATA-binding protein homologs, the general transcription factor TBP and a related factor called TLF. Four models have been proposed for the role of TLF in RNA polymerase II (Pol II) transcription: (1) TLF and TBP function redundantly, (2) TLF antagonizes TBP, (3) TLF is a ti...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Caenorhabditis elegans
Share to Caenorhabditis elegans Proteins
Share to DNA-Binding Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Embryo, Nonmammalian

Share to Gene Expression Regulation, Developmental

Share to Promoter Regions, Genetic

Share to RNA Polymerase II

Share to Transcriptional Activation

Source

Identifiers

PMID: 11030349
DOI: 10.1016/s1097-2765(00)00068-x

Genes

TBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-11030349-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The TBP-like factor CeTLF is required to activate RNA polymerase II transcription during C. elegans embryogenesis.PMID 11030349Read ↗

TBP-like factor is required for embryonic RNA polymerase II transcription in C. elegans.Semantic proximity Read ↗

An extensive requirement for transcription factor IID-specific TAF-1 in Caenorhabditis elegans embryonic transcription.Semantic proximity Read ↗

The double-stranded DNA-binding proteins TEBP-1 and TEBP-2 form a telomeric complex with POT-1Semantic proximity Read ↗

The double-stranded DNA-binding proteins TEBP-1 and TEBP-2 form a telomeric complex with POT-1.Semantic proximity Read ↗

ELT-2 is the predominant transcription factor controlling differentiation and function of the C. elegans intestine, from embryo to adult.Semantic proximity Read ↗

Missing women—revisitedSemantic proximity Read ↗

CDK-9/cyclin T (P-TEFb) is required in two postinitiation pathways for transcription in the C. elegans embryo.Semantic proximity Read ↗

The C. elegans maternal-effect gene clk-2 is essential for embryonic development, encodes a protein homologous to yeast Tel2p and affects telomere length.Semantic proximity Read ↗

Vertebrate TBP-like protein (TLP/TRF2/TLF) stimulates TATA-less terminal deoxynucleotidyl transferase promoters in a transient reporter assay, and TFIIA-binding capacity of TLP is required for this function.Semantic proximity Read ↗

TBPL2/TFIIA complex establishes the maternal transcriptome through oocyte-specific promoter usage.Semantic proximity Read ↗

dELL is an essential RNA polymerase II elongation factor with a general role in development.Semantic proximity Read ↗

Drosophila TRF2 and TAF9 regulate lipid droplet size and phospholipid fatty acid composition.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.