Article
Breast Cancer Is Associated with Increased HLA-DRB1*11:01 and HLA-DRB1*10:01 Allele Frequency in a Population of Patients from Central Italy.
Immunological investigations - 1 Jul 2020
Aureli Anna, Canossi Angelica, Del Beato Tiziana, Buonomo Oreste, Rossi Piero, Roselli Mario, Papola Franco, Marziani Beatrice, Sconocchia Giuseppe
Abstract excerpt
The relationship between HLA-DRB1 allele polymorphism and breast cancer (BC) development is still unclear and needs further investigation. To address this issue, we analyzed HLA-DRB1 allele frequency (AF) by sequence-based typing (SBT) in 47 patients from central Italy with BC and 156 sex and age-matched healthy controls. Two hundred ninety-seven individuals from the same region were utilized as historical...
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