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Article

Identification and characterization of a silencer regulatory element in the 3'-flanking region of the murine CD46 gene.

The Biochemical journal - 15 Oct 2000

Nomura M, Tsujimura A, Begum N A, Matsumoto M, Wabiko H, Toyoshima K, Seya T

Abstract excerpt

The murine membrane cofactor protein (CD46) gene is expressed exclusively in testis, in contrast to human CD46, which is expressed ubiquitously. To elucidate the mechanism of differential CD46 gene expression among species, we cloned entire murine CD46 genomic DNA and possible regulatory regions were placed in the flanking region of the luciferase reporter gene. The reporter gene assay revealed a silencing...

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Identifiers

PMID: 11023821
PMCID: PMC1221371

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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