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Article

A Functional Interaction between CD46 and DLG4

1 Feb 2002

Abstract excerpt

Using a yeast two-hybrid screen, we identified a physical interaction between CD46 and DLG4. CD46 is a ubiquitous human cell-surface receptor for the complement components C3b and C4b and for measles virus and human herpesvirus 6. DLG4 is a scaffold protein important for neuronal signaling and is homologous to the Drosophila tumor suppressor DLG. We show that an interaction between CD46 and DLG4 is important for...

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PMID: 11714708
DOI: 10.1074/jbc.m108479200

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