Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cytotoxic Anthracycline Metabolites from a Recombinant Streptomyces

16 May 2018

Abstract excerpt

The C7 (C9 or C10)- O - l- rhodosamine-bearing anthracycline antibiotic cytorhodins and their biosynthetic intermediates were recently isolated from Streptomyces sp. SCSIO 1666. Cosmid p17C4 from the Streptomyces lydicus genomic library, which harbors both the biosynthetic genes for l- rhodinose (or 2-deoxy- l -fucose) and its glycosyltransferase (encoded by slgG), was introduced into SCSIO 1666 to yield the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Treatment and Pharmacology
Share to Chemotherapy-induced cardiotoxicity and mitigation
Share to Microbial Natural Products and Biosynthesis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29767975
DOI: 10.1021/acs.jnatprod.8b00212

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cytotoxic Anthracycline Metabolites from a Recombinant StreptomycesPMID 29767975Read ↗

Biosynthetic AnthracyclinesSemantic proximity Read ↗

A Novel Peptide Antibiotic Produced by Streptomyces roseoflavus Strain INA-Ac-5812 With Directed Activity Against Gram-Positive BacteriaSemantic proximity Read ↗

Microbial glycosidation of some anthracycline antibiotics by an antibiotic-negative mutant of aclarubicin producer.Semantic proximity Read ↗

Ribosome engineering and fermentation optimization leads to overproduction of tiancimycin A, a new enediyne natural product from Streptomyces sp. CB03234.Semantic proximity Read ↗

Metabolic engineering of Streptomyces peucetius for biosynthesis of N,N-dimethylated anthracyclinesSemantic proximity Read ↗

Role of sgcR3 in positive regulation of enediyne antibiotic C-1027 production of Streptomyces globisporus C-1027.Semantic proximity Read ↗

A gene cluster from Streptomyces galilaeus involved in glycosylation of aclarubicin.Semantic proximity Read ↗

Combinatorial biosynthesis of lipopeptide antibiotics in Streptomyces roseosporusSemantic proximity Read ↗

Antibacterial and Cytotoxic New Napyradiomycins from the Marine-Derived Streptomyces sp. SCSIO 10428Semantic proximity Read ↗

Deoxysugar Methylation during Biosynthesis of the Antitumor Polyketide Elloramycin by Streptomyces olivaceusSemantic proximity Read ↗

Expanding the Chemical Diversity of the Antitumoral Compound Mithramycin by Combinatorial Biosynthesis and Biocatalysis: The Quest for Mithralogs with Improved Therapeutic WindowSemantic proximity Read ↗

New rhodomycin analogs, SS-288A and SS-288B, produced by a Streptomyces violaceus A262 mutant.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.