Article
Analysis of BRCA1 involvement in breast cancer in Indian women.
Journal of biosciences - 1 Mar 2000
Pestonjamasp P H, Mittra I
Abstract excerpt
The involvement of the familial breast-ovarian cancer gene (BRCA1) in the molecular pathogenesis of breast cancer among Indian women is unknown. We have used a set of microsatellite polymorphisms to examine the frequency of allele loss at the BRCA1 region on chromosome 17q21, in a panel of 80 human breast tumours. Tumour and blood leukocyte/normal tissue DNA from a series of 80 patients with primary breast cancer...
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