Article
Application of the heteroduplex mobility assay (HMA) for the investigation of the genomic diversity among noroviruses in environmental samples.
Journal of virological methods - 1 Sept 2004
Green Jonathan, Gallimore Chris I, Shore Jane, Sellwood Jane, Brown David W G
Abstract excerpt
Recent studies have demonstrated the widespread contamination of river and seawater with noroviruses (NV), often with more than one strain. The heteroduplex mobility assay (HMA) in which amplicons from study samples are hybridised (by denaturing and reannealing) to amplicons from reference strains and resolved by electrophoresis, has the potential to provide a simple and rapid means to identify samples containing...
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