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Article

Combined hepatocellular-cholangiocarcinoma: what the radiologist needs to know about biphenotypic liver carcinoma.

Abdominal imaging - 1 Apr 2014

Shetty Anup S, Fowler Kathryn J, Brunt Elizabeth M, Agarwal Saurabh, Narra Vamsi R, Menias Christine O

Abstract excerpt

Combined hepatocellular-cholangiocarcinoma (CHC), also referred to as primary liver carcinoma (PLC) with biphenotypic differentiation, is an increasingly recognized subtype of malignant PLC encompassing varying morphologic forms thought to arise either from progenitor cell lineage or dedifferentiation of mature liver cells. Tumor cells express both biliary and hepatocellular markers by immunohistochemistry, and...

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Identifiers

PMID: 24407728
DOI: 10.1007/s00261-013-0069-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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