Article
Ribosomal protein L2 is involved in the association of the ribosomal subunits, tRNA binding to A and P sites and peptidyl transfer.
The EMBO journal - 2 Oct 2000
Diedrich G, Spahn C M, Stelzl U, Schäfer M A, Wooten T, Bochkariov D E, Cooperman B S, Traut R R, Nierhaus K H
Abstract excerpt
Ribosomal proteins L2, L3 and L4, together with the 23S RNA, are the main candidates for catalyzing peptide bond formation on the 50S subunit. That L2 is evolutionarily highly conserved led us to perform a thorough functional analysis with reconstituted 50S particles either lacking L2 or harboring a mutated L2. L2 does not play a dominant role in the assembly of the 50S subunit or in the fixation of the 3'-ends...
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