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Article

The evolution of senescence under curtailed life span in laboratory populations of Musca domestica (the housefly).

Heredity - 1 Aug 2000

Reed D H, Bryant E H

Abstract excerpt

The evolution of senescence may be explained by two different, but not mutually exclusive, genetic mechanisms. The antagonistic pleiotropy hypothesis predicts that senescence is a consequence of the fixation of alleles with pleiotropic effects favouring early life fitness, but bearing a cost in later life. The mutation-accumulation hypothesis attributes senescence to the accumulation of deleterious mutations with...

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PMID: 11012712
DOI: 10.1046/j.1365-2540.2000.00737.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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