Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immunological transitions in response to antigenic mutation during viral infection.

International immunology - 1 Oct 2000

Wahl L M, Bittner B, Nowak M A

Abstract excerpt

Antigenic variation is an important factor in viral persistence and disease progression. We analyze immunological changes which occur in response to antigenic mutation during chronic viral infection. Using an established model of viral and immune system dynamics, we determine which qualitative shifts in the immune response can be elicited by the appearance of a new mutant. We find that antigenic mutation can...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Viral
Share to Chronic Disease
Share to Epitopes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Virus Diseases

Source

Identifiers

PMID: 11007754
DOI: 10.1093/intimm/12.10.1371

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immunological transitions in response to antigenic mutation during viral infection.PMID 11007754Read ↗

Antigenic drift: Understanding COVID-19.Semantic proximity Read ↗

Antigenic variation and the within-host dynamics of parasites.Semantic proximity Read ↗

Superinfection as a driver of genomic diversification in antigenically variant pathogens.Semantic proximity Read ↗

Modelling the role of immunity in reversion of viral antigenic sitesSemantic proximity Read ↗

The evolutionary dynamics of receptor binding avidity in influenza A: a mathematical model for a new antigenic drift hypothesis.Semantic proximity Read ↗

Within-host viral evolution varies with T cell receptor repertoire diversity independently of viral mutation ratesSemantic proximity Read ↗

A quantitative quasispecies theory-based model of virus escape mutation under immune selection.Semantic proximity Read ↗

Pathogen evolution and the immunological niche.Semantic proximity Read ↗

Plasticity of T cell memory responses to viruses.Semantic proximity Read ↗

The Evolution and Genetics of Virus Host ShiftsSemantic proximity Read ↗

Within-host stochastic emergence dynamics of immune-escape mutants.Semantic proximity Read ↗

Antigenic evolution of viruses in host populations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.