Article
The transcriptional factor LBP-1c/CP2/LSF gene on chromosome 12 is a genetic determinant of Alzheimer's disease.
Human molecular genetics - 22 Sept 2000
Lambert J C, Goumidi L, Vrièze F W, Frigard B, Harris J M, Cummings A, Coates J, Pasquier F, Cottel D, Gaillac M, St Clair D, Mann D M, Hardy J, Lendon C L, Amouyel P, Chartier-Harlin M C
Abstract excerpt
Although the varepsilon4 allele of the apolipoprotein E gene appears as an important biological marker for Alzheimer's disease (AD) susceptibility, other genetic determinants are clearly implicated in the AD process. Here, we propose that a genetic variation in the transcriptional factor LBP-1c/CP2/LSF gene, located close to the LRP locus, is a genetic susceptibility factor for AD. We report an association...
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