Article
Association of polymorphism in the transcription factor LBP-1c/CP2/LSF gene with Alzheimer's disease and major depression.
Dementia and geriatric cognitive disorders - 1 Jan 2006
Schahab Schamim, Heun Reinhard, Schmitz Sandra, Maier Wolfgang, Kölsch Heike
Abstract excerpt
The transcription factor LBP-1c/CP2/LSF (LBP-1c) is a candidate gene for Alzheimer's disease (AD) because it is located in a putative hotspot for an AD risk gene on chromosome 12. We investigated the effect of LBP-1c polymorphism on the risk of AD in 162 AD patients, 180 patients with major depression as hospitalized controls and 225 healthy subjects. We observed no significant association of the LBP-1c A allele...
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