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Article

Routing of the aquaporin-2 water channel in health and disease.

European journal of cell biology - 1 Aug 2000

Deen P M, van Balkom B W, Kamsteeg E J

Abstract excerpt

The identification of the first water channel in 1991 opened up a new field in cell biology and physiology that significantly increased our understanding of mammalian water balance regulation. Since then, nine other mammalian aquaporins have been identified. Although the physiological significance of many aquaporins is still to be elucidated, it has been clearly established for aquaporin-2. This water channel,...

Topics

Animals
Aquaporin 2
Aquaporin 6
Aquaporins
Arginine Vasopressin
Cell Compartmentation
Diabetes Insipidus, Nephrogenic
Humans
Hypotension
Kidney Tubules, Collecting
Mutation
Protein Transport

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Signal Transduction

Water-Electrolyte Balance

Source

Identifiers

PMID: 11001488
DOI: 10.1078/0171-9335-00075

Genes

AQP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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