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Article

The vasopressin-aquaporin-2 pathway syndromes.

Handbook of clinical neurology - 1 Jan 2021

Valenti Giovanna, Tamma Grazia

Abstract excerpt

Vasopressin is the key hormone involved in water conservation and regulation of water balance, essential for life. In the renal collecting duct, vasopressin binds to the V2 receptor, increasing water permeability through activation of aquaporin-2 redistribution to the luminal membrane. This mechanism promotes rapid water reabsorption, important for immediate survival; however, only recently it has become clear...

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PMID: 34238461
DOI: 10.1016/B978-0-12-820683-6.00018-X

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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