Article
Familial Wilms' tumor with neural elements: characterization by histology, immunohistochemistry, and genetic analysis.
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society - 1 Jan 2000
Hussong J W, Perkins S L, Huff V, McDonald J M, Pysher T J, Beckwith J B, Coffin C M
Abstract excerpt
Wilms' tumor (WT) is the most common renal malignancy of children. While most occur sporadically, a small percentage are familial or occur as part of a developmental syndrome. Classic WTs exhibit a triphasic histologic pattern composed of blastema, epithelium, and stroma. Occasionally, heterologous elements may also be observed. In this study we investigated a series of four WTs that occurred within a single...
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