Identical genetic changes in different histologic components of Wilms' tumors.

doi:10.1093/jnci/89.15.1148

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Article

Identical genetic changes in different histologic components of Wilms' tumors.

Journal of the National Cancer Institute - 6 Aug 1997

Zhuang Z, Merino M J, Vortmeyer A O, Bryant B, Lash A E, Wang C, Deavers M T, Shelton W F, Kapur S, Chandra R S

Abstract excerpt

BACKGROUND: In young children and infants, Wilms' tumor is the most common cancer of the kidney. Wilms' tumor exhibits heterogeneous histopathologic features, consisting of rapidly proliferating blastemal and epithelial cells and a stromal component that has heterologous elements (e.g., cartilage...

Topics

Alleles
Chromosome Deletion
DNA Probes
Gene Deletion
Gene Expression Regulation, Neoplastic
Genes, Wilms Tumor
Heterozygote
Humans
Kidney Neoplasms
Polymerase Chain Reaction
Transcription, Genetic
Wilms Tumor

Source

Open in PubMed

Identifiers

PMID: 9262253
DOI: 10.1093/jnci/89.15.1148

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9262253-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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