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Article

Leader proteinase of the beet yellows closterovirus: mutation analysis of the function in genome amplification.

Journal of virology - 1 Oct 2000

Peng C W, Dolja V V

Abstract excerpt

The beet yellows closterovirus leader proteinase (L-Pro) possesses a C-terminal proteinase domain and a nonproteolytic N-terminal domain. It was found that although L-Pro is not essential for basal-level replication, deletion of its N-terminal domain resulted in a 1, 000-fold reduction in RNA accumulation. Mutagenic analysis of the N-terminal domain revealed its structural flexibility except for the...

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Identifiers

PMID: 11000252
DOI: 10.1128/jvi.74.20.9766-9770.2000
PMCID: PMC112412

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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