Article
Leader proteinase of beet yellows virus functions in long-distance transport.
Journal of virology - 1 Mar 2003
Peng Chih-Wen, Napuli Alberto J, Dolja Valerian V
Abstract excerpt
The 66-kDa leader proteinase (L-Pro) of the Beet yellows virus (BYV) possesses a nonconserved N-terminal domain and a conserved, papain-like C-terminal domain. Previous work revealed that the N-terminal domain functions in RNA amplification, whereas the C-terminal domain is required for autoproteolysis. Alanine-scanning mutagenesis was applied to complete the functional analysis of L-Pro throughout the virus life...
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