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Article

Tropomyosin-dependent filament formation by a polymerization-defective mutant yeast actin (V266G,L267G).

The Journal of biological chemistry - 22 Dec 2000

Wen K K, Kuang B, Rubenstein P A

Abstract excerpt

A major function of tropomyosin (TPM) in nonmuscle cells may be stabilization of F-actin by binding longitudinally along the actin filament axis. However, no clear evidence exists in vitro that TPM can significantly affect the critical concentration of actin. We previously made a polymerization-defective mutant actin, GG (V266G, L267G). This actin will not polymerize alone at 25 degrees C but will in the presence...

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Source

Identifiers

PMID: 10998421
DOI: 10.1074/jbc.M007201200

Genes

TPM1
TPM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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