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Article

Role of intermonomer ionic bridges in the stabilization of the actin filament.

The Journal of biological chemistry - 12 Dec 2008

Stokasimov Ema, McKane Melissa, Rubenstein Peter A

Abstract excerpt

Filament formation is required for most of the functions of actin. However, the intermonomer interactions that stabilize F-actin have not been elucidated because of a lack of an F-actin crystal structure. The Holmes muscle actin model suggests that an ionic interaction between Arg-39 of one monomer and Glu-167 of an adjacent monomer in the same strand contributes to this stabilization. Yeast actin has an Ala-167...

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Identifiers

PMID: 18945676
DOI: 10.1074/jbc.M804419200
PMCID: PMC2596410

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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