Article
Genetic analysis of lifespan in hybrid progeny derived from the SAMP1 mouse strain with accelerated senescence.
Mechanisms of ageing and development - 1 Sept 2000
Guo Z, Toichi E, Hosono M, Hosokawa T, Hosokawa M, Higuchi K, Mori M
Abstract excerpt
The SAMP1 mouse, a senescence-accelerated mouse prone (SAMP) strain, shows accelerated senescence coupled with a short lifespan as a genetic trait, and has been used in gerontological research. The accelerated senescence and short lifespan of SAMP strains is considered to be under the control of multiple genes. To identify the chromosomal regions encompassing the genes for the accelerated senescence and short...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.