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Article

Genetic characterization of senescence-accelerated mouse (SAM).

Experimental gerontology - 1 Jan 2000

Higuchi K

Abstract excerpt

The Senescence-Accelerated Mouse (SAM) strains are unique and appropriate models for genetic studies on aging because the SAMP strains have an "accelerated senescence" phenotype for which the SAMR strains are controls, and each SAMP strain has a strain-specific age-associated disorder. Furthermore, because they have gone through sufficient generations of sister-brother mating, they can be considered inbred...

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PMID: 9088910
DOI: 10.1016/s0531-5565(96)00060-5

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