Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A novel model of spontaneous otitis media with effusion (OME) in the Oxgr1 knock-out mouse.

International journal of pediatric otorhinolaryngology - 1 Jan 2013

Kerschner Joseph E, Hong Wenzhou, Taylor Steven R, Kerschner John A, Khampang Pawjai, Wrege Kay C, North Paula E

Abstract excerpt

OBJECTIVE: A novel mouse model with a specific genetic mutation in a G protein coupled receptor (GPCR) encoded by the Oxgr1 gene results in a predisposition to spontaneous otitis media with effusion. As a primary component of interest in OME, mucin expression was examined in this model to assess...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biopsy, Needle
Share to Evoked Potentials, Auditory, Brain Stem
Share to Immunohistochemistry

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Knockout

Share to Mucins

Share to Random Allocation

Share to Receptors, Purinergic P2

Share to Reverse Transcriptase Polymerase Chain Reaction

Source

Open in PubMed Open full text

Identifiers

PMID: 23200873
DOI: 10.1016/j.ijporl.2012.09.037
PMCID: PMC3535456

Genes

ABR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23200873-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A novel model of spontaneous otitis media with effusion (OME) in the Oxgr1 knock-out mouse.PMID 23200873Read ↗

Unraveling the genetics of otitis media: from mouse to human and back again.Semantic proximity Read ↗

Otitis media in the Tgif knockout mouse implicates TGFβ signalling in chronic middle ear inflammatory disease.Semantic proximity Read ↗

Oto-endoscopy: a reliable and validated technique for phenotyping otitis media in the mouse.Semantic proximity Read ↗

What have we learned from murine models of otitis media?Semantic proximity Read ↗

Panel 4: Recent advances in otitis media in molecular biology, biochemistry, genetics, and animal models.Semantic proximity Read ↗

MUC5ACExpression in Human Middle Ear Epithelium of Patients With Otitis MediaSemantic proximity Read ↗

A mutation in the F-box gene, Fbxo11, causes otitis media in the Jeff mouse.Semantic proximity Read ↗

Current Understanding of Host Genetics of Otitis MediaSemantic proximity Read ↗

A mouse-to-man candidate gene study identifies association of chronic otitis media with the loci TGIF1 and FBXO11.Semantic proximity Read ↗

Otitis media in a new mouse model for CHARGE syndrome with a deletion in the Chd7 gene.Semantic proximity Read ↗

Vlgr1 knockout mice show audiogenic seizure susceptibility.Semantic proximity Read ↗

IgE sensitization, respiratory allergy symptoms, and heritability independently increase the risk of otitis media with effusion.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.