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Article

Mutations at lysine 525 of inducible nitric-oxide synthase affect its Ca2+-independent activity.

The Journal of biological chemistry - 17 Nov 2000

Lee S J, Beckingham K, Stull J T

Abstract excerpt

Calmodulin binding to inducible nitric-oxide synthase may play an important role in its Ca(2+)-independent activity. Studies of inducible nitric-oxide synthase chimeras containing the calmodulin binding sequence of neuronal or endothelial nitric-oxide synthases show that the calmodulin binding sequence of inducible nitric-oxide synthase is necessary but not sufficient for the Ca(2+)-independent activity. The...

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Identifiers

PMID: 10978319
DOI: 10.1074/jbc.M003935200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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