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Article

Versatile regulation of neuronal nitric oxide synthase by specific regions of its C-terminal tail.

Biochemistry - 18 Dec 2007

Tiso Mauro, Tejero Jesús, Panda Koustubh, Aulak Kulwant S, Stuehr Dennis J

Abstract excerpt

The C-terminal tail (CT) of neuronal nitric oxide synthase (nNOS) is a regulatory element that suppresses nNOS activities in the absence of bound calmodulin (CaM). A crystal structure of the nNOS reductase domain (nNOSr) (Garcin, E. D., Bruns, C. M., Lloyd, S. J., Hosfield, D. J., Tiso, M., Gachhui, R., Stuehr, D. J., Tainer, J. A., and Getzoff, E. D. (2004) J. Biol. Chem. 279, 37918-37927) revealed how the first...

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PMID: 18020458
DOI: 10.1021/bi701646k

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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