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Article

An isochore transition in the NF1 gene region coincides with a switch in the extent of linkage disequilibrium.

American journal of human genetics - 1 Oct 2000

Eisenbarth I, Vogel G, Krone W, Vogel W, Assum G

Abstract excerpt

Whole-genome association studies will be a powerful tool to identify genes responsible for common human diseases. A crucial task for association-mapping studies is the evaluation of the relationship between linkage disequilibrium (LD) and physical distance for the genomic region under study. Since it is known that the extent of LD is nonuniformly distributed throughout the human genome, the required marker...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 10978227
DOI: 10.1086/303085
PMCID: PMC1287892

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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