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Article

An isochore map of human chromosomes.

Genome research - 1 Apr 2006

Costantini Maria, Clay Oliver, Auletta Fabio, Bernardi Giorgio

Abstract excerpt

Isochores are large DNA segments (>>300 kb on average) that are characterized by an internal variation in GC well below the full variation seen in the mammalian genome. Precisely defining in terms of size and composition as well as mapping the isochores on human chromosomes have, however, remained largely unsolved problems. Here we used a very simple approach to segment the human chromosomes de novo, based on...

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Identifiers

PMID: 16597586
DOI: 10.1101/gr.4910606
PMCID: PMC1457033

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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