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Article

Distribution and high frequency of novel alleles at NF1 polymorphic markers in the Italian population.

Molecular and cellular probes - 1 Dec 1999

Natacci F, Colapietro P, Riva P, Corrado L, Rossi L N, Maninetti M M, Casciati M C, Zambrino C a, Lanzi G, Larizza L

Abstract excerpt

Segregation analysis of Neurofibromatosis type 1 (NF1) intragenic polymorphisms is a useful diagnostic tool for linkage analysis in familial cases and for the exclusion/detection of deletion in sporadic patients. We performed a segregation analysis of intragenic NF1 polymorphic markers in an Italian NF1 population consisting of 17 familial and 41 sporadic cases, for a total of 79 affected and 105 unaffected...

Topics

Alleles
Biomarkers, Tumor
Female
Gene Frequency
Genes, Neurofibromatosis 1
Genetic Markers
Humans
Italy
Male
Neurofibromatosis 1
Pedigree

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Genetic

Source

Identifiers

PMID: 10657145
DOI: 10.1006/mcpr.1999.0268

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