["Cold" spots in hypervariable segment 1 of human mitochondrial DNA].

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Article

["Cold" spots in hypervariable segment 1 of human mitochondrial DNA].

Molekuliarnaia biologiia - 1 Jan 2000

Maliarchuk B A

Abstract excerpt

Analysis of distribution of mutations in hypervariable segment 1 (HVS1) of mitochondrial DNA (mtDNA) in data set of more than 37,000 individuals, representing different regions of the world, allowed one to estimate the mutation processes intensity and peculiarity of mtDNA "cold" spots distribution. Results of analysis of structure-function organization and variability of the mtDNA fragment under study revealed...

Topics

DNA Mutational Analysis
DNA, Mitochondrial
Humans
Mutation

Source

Open in PubMed

Identifiers

PMID: 18702303

Genes

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