Article
Downregulation of glutamate receptor subunit 2(3) in subependymal giant-cell tumor.
Pediatric neurology - 1 Jul 2000
Arai Y, Takashima S, Becker L E
Abstract excerpt
Immunohistochemical techniques were used to investigate the expression of glutamate receptor (GluR) subunits in samples of brain resected from children with and without tuberous sclerosis, using antibody to an epitope common to GluR subunits 2 and 3 [2(3)]. Our purpose was to characterize the phe...
Topics
- Adolescent
- Adult
- Astrocytoma
- Blotting, Western
- Brain Neoplasms
- Case-Control Studies
- Child
- Child, Preschool
- Down-Regulation
- Female
- Gene Expression Regulation, Neoplastic
- Giant Cells
- Gliosis
- Humans
- Immunohistochemistry
- Male
- Phenotype
- Receptors, Metabotropic Glutamate