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Article

Pathological Findings of a Subependymal Giant Cell Astrocytoma Following Treatment With Rapamycin.

Pediatric neurology - 1 Sept 2015

Cheng Sylvia, Hawkins Cynthia, Taylor Michael D, Bartels Ute

Abstract excerpt

BACKGROUND: Tuberous sclerosis complex is a heritable multisystem disorder associated with genes involved in the formation of a tumor-suppressor complex acting through the Ras homologue enriched in brain protein to limit activation of the mammalian target of rapamycin complex I. Mutations in these genes result in enhanced mammalian target of rapamycin signaling and may cause neurological manifestations including...

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Identifiers

PMID: 26173783
DOI: 10.1016/j.pediatrneurol.2015.05.020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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