Article
Apoliprotein E and multiple sclerosis: impact of the epsilon-4 allele on susceptibility, clinical type and progression rate.
Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Aug 2000
Høgh P, Oturai A, Schreiber K, Blinkenberg M, Jørgensen O S, Ryder L, Paulson O B, Sørensen P S, Knudsen G M
Abstract excerpt
The purpose of this study was to investigate the relation between APOE genotype and Multiple Sclerosis (MS) in a genetically homogeneous population. We examined 240 patients consulting the MS-clinic during a period of 3 years (1996 - 1999). The mean age of the patients was 41.7 years (range 19 - 80 Y, SD 10.0 Y). As a measure of the progression rate (PR) the last registered Expanded Disability Status Scale (EDSS)...
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