Article
Consistent long-range linkage disequilibrium generated by admixture in a Bantu-Semitic hybrid population.
American journal of human genetics - 1 Oct 2000
Wilson J F, Goldstein D B
Abstract excerpt
Both the optimal marker density for genome scans in case-control association studies and the appropriate study design for the testing of candidate genes depend on the genomic pattern of linkage disequilibrium (LD). In this study, we provide the first conclusive demonstration that the diverse demographic histories of human populations have produced dramatic differences in genomewide patterns of LD. Using a panel...
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