Article
Markers informative for ancestry demonstrate consistent megabase-length linkage disequilibrium in the African American population.
Human genetics - 1 Aug 2003
Collins-Schramm Heather E, Chima Bill, Operario Darwin J, Criswell Lindsey A, Seldin Michael F
Abstract excerpt
Admixture mapping is a potentially powerful tool for mapping complex genetic diseases. For application of this method, admixed individuals must have genomes composed of large segments derived intact from each founding population. Such segments are thought to be present in African Americans (AA) and should be demonstrable by examination of linkage disequilibrium (LD). Previous studies using a variety of...
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