Article
Expression and antitumor effects of TRAIL in human cholangiocarcinoma.
Hepatology (Baltimore, Md.) - 1 Sept 2000
Tanaka S, Sugimachi K, Shirabe K, Shimada M, Wands J R
Abstract excerpt
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)/Apo2L has been recently identified as important in promoting programmed cell death in breast and colon adenocarcinomas. In this study, we investigated the expression and therapeutic potential of TRAIL in cholangiocarcinoma, one of the most devastating human hepatic malignancies. Expression of TRAIL receptors was determined in 13 patients with...
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