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Article

The N terminus of the centromere H3-like protein Cse4p performs an essential function distinct from that of the histone fold domain.

Molecular and cellular biology - 1 Sept 2000

Chen Y, Baker R E, Keith K C, Harris K, Stoler S, Fitzgerald-Hayes M

Abstract excerpt

Cse4p is an evolutionarily conserved histone H3-like protein that is thought to replace H3 in a specialized nucleosome at the yeast (Saccharomyces cerevisiae) centromere. All known yeast, worm, fly, and human centromere H3-like proteins have highly conserved C-terminal histone fold domains (HFD) but very different N termini. We have carried out a comprehensive and systematic mutagenesis of the Cse4p N terminus to...

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Identifiers

PMID: 10958698
DOI: 10.1128/MCB.20.18.7037-7048.2000
PMCID: PMC88778

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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