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Article

Cell cycle activation by c-myc in a Burkitt lymphoma model cell line

1 Jan 2000

Abstract excerpt

The product of the proto-oncogene c-myc (myc) is a potent activator of cell proliferation. In Burkitt lymphoma (BL), a human B-cell tumor, myc is consistently found to be transcriptionally activated by chromosomal translocation. The mechanisms by which myc promotes cell cycle progression in B-cells is not known. As a model for myc activation in BL cells, we have established a human EBV-EBNA1 positive B-cell line,...

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Identifiers

PMID: 10956386
DOI: 10.1002/1097-0215(20000915)87:6<787::aid-ijc4>3.0.co;2-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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