Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association between PON1 L/M55 polymorphism and plasma lipoproteins in two Canadian aboriginal populations.

Clinical chemistry and laboratory medicine - 1 May 2000

Fanella S, Harris S B, Young T K, Hanley A J, Zinman B, Connelly P W, Hegele R A

Abstract excerpt

Serum paraoxonase circulates on a subfraction of high density lipoproteins and appears to use phospholipids on both low and high density lipoprotein particles as a physiological substrate. This functional relationship could explain the reported associations between common variation in the PON1 gene--at codons 55 and 192--and phenotypes related to atherosclerosis and lipoprotein metabolism. We evaluated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aryldialkylphosphatase
Share to Canada

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cholesterol

Share to Cholesterol, HDL

Share to Cholesterol, LDL

Share to Esterases

Share to Indians, North American

Source

Identifiers

PMID: 10952224
DOI: 10.1515/CCLM.2000.060

Genes

PON1
PON2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association between PON1 L/M55 polymorphism and plasma lipoproteins in two Canadian aboriginal populations.PMID 10952224Read ↗

Genetic variation in paraoxonase-2 is associated with variation in plasma lipoproteins in Canadian Oji-Cree.Semantic proximity Read ↗

Relationship between high-density lipoprotein paraoxonase gene M/L55 polymorphism and carotid atherosclerosis differs in smoking and nonsmoking men.Semantic proximity Read ↗

Paraoxonase 1 (PON1)-L55M among common variants in the coding region of the paraoxonase gene family may contribute to the glycemic control in type 2 diabetes.Semantic proximity Read ↗

Paraoxonase polymorphisms PON1 192 and 55 and longevity in Italian centenarians and Irish nonagenarians. A pooled analysis.Semantic proximity Read ↗

PON1 M/L55 mutation protects high-risk patients against coronary artery disease.Semantic proximity Read ↗

Human paraoxonase 1 gene polymorphisms and the risk of coronary heart disease: a community-based study.Semantic proximity Read ↗

Analysis of paraoxonase (PON1) L55M status requires both genotype and phenotype.Semantic proximity Read ↗

Effect of the human serum paraoxonase 55 and 192 genetic polymorphisms on the protection by high density lipoprotein against low density lipoprotein oxidative modification.Semantic proximity Read ↗

Common genomic variants associated with variation in plasma lipoproteins in young aboriginal Canadians.Semantic proximity Read ↗

Serum paraoxonase (PON1) 55 and 192 polymorphism and paraoxonase activity and concentration in non-insulin dependent diabetes mellitus.Semantic proximity Read ↗

Paraoxonase 1 R/Q alleles are associated with differential accumulation of saturated versus 20:5n3 fatty acid in human adipose tissue.Semantic proximity Read ↗

Can paraoxonase 1 polymorphisms (L55 M and Q192 R) protect children with type 1 diabetes against lipid abnormalities?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.