Article
Serum paraoxonase (PON1) 55 and 192 polymorphism and paraoxonase activity and concentration in non-insulin dependent diabetes mellitus.
Atherosclerosis - 1 Aug 1998
Mackness B, Mackness M I, Arrol S, Turkie W, Julier K, Abuasha B, Miller J E, Boulton A J, Durrington P N
Abstract excerpt
Human serum paraoxonase (PON1) is located on high density lipoprotein and has been implicated in the detoxification of organophosphates and possibly in the prevention of low density lipoprotein lipid peroxidation. PON1 has two genetic polymorphisms both due to amino acid substitution, one involving glutamine (A genotype) and arginine (B genotype) at position 192 and the other leucine (L genotype) and methionine...
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