Serum paraoxonase (PON1) 55 and 192 polymorphism and paraoxonase activity and concentration in non-insulin dependent diabetes mellitus.

doi:10.1016/s0021-9150(98)00095-1

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Article

Serum paraoxonase (PON1) 55 and 192 polymorphism and paraoxonase activity and concentration in non-insulin dependent diabetes mellitus.

Atherosclerosis - 1 Aug 1998

Mackness B, Mackness M I, Arrol S, Turkie W, Julier K, Abuasha B, Miller J E, Boulton A J, Durrington P N

Abstract excerpt

Human serum paraoxonase (PON1) is located on high density lipoprotein and has been implicated in the detoxification of organophosphates and possibly in the prevention of low density lipoprotein lipid peroxidation. PON1 has two genetic polymorphisms both due to amino acid substitution, one involvi...

Topics

Adult
Aryldialkylphosphatase
Diabetes Mellitus, Type 2
Esterases
Female
Genotype
Humans
Lipids
Lipoproteins
Male
Middle Aged
Osmolar Concentration
Polymorphism, Genetic
Reference Values

Source

Open in PubMed

Identifiers

PMID: 9712341
DOI: 10.1016/s0021-9150(98)00095-1

Genes

PON1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9712341-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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