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Article

Role of Inducible Nitric Oxide Synthase in Resistance toMycobacterium lepraein Mice

1 Sept 2000

Abstract excerpt

The manifestation of leprosy in humans is largely determined by host immunity to Mycobacterium leprae and is a model for immunoregulation in a human disease. However, animal models available for exploration of the leprosy spectrum are inadequate. This study explored M. leprae infection in mice deficient in inducible nitric oxide synthase, and this report describes elements resembling borderline tuberculoid...

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PMID: 10948185
DOI: 10.1128/iai.68.9.5462-5465.2000

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