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Analysis of mtDNA copy number and composition of single mitochondrial particles using flow cytometry and PCR.

Experimental cell research - 25 Aug 2000

Cavelier L, Johannisson A, Gyllensten U

Abstract excerpt

Mitochondrial DNA (mtDNA) is a multicopy, maternally inherited, genome. Individuals frequently carry a mixture of genetically distinct mtDNA molecules whose proportions may vary between sexual generations or among tissues from the same individual. Analyses of the genetic composition of mitochondria have previously relied on electron microscopy and have not permitted the genotype of single mitochondria to be...

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PMID: 10942580
DOI: 10.1006/excr.2000.4949

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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