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Article

Quantitative analysis of somatic mitochondrial DNA mutations by single-cell single-molecule PCR.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2009

Kraytsberg Yevgenya, Bodyak Natalya, Myerow Susan, Nicholas Alexander, Ebralidze Konstantin, Khrapko Konstantin

Abstract excerpt

Mitochondrial genome integrity is an important issue in somatic mitochondrial genetics. Development of quantitative methods is indispensable to somatic mitochondrial genetics as quantitative studies are required to characterize heteroplasmy and mutation processes, as well as their effects on phenotypic developments. Quantitative studies include the identification and measurement of the load of pathogenic and...

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PMID: 19513684
DOI: 10.1007/978-1-59745-521-3_21

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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