Article
Nicotinic receptor channelopathies and epilepsy.
Pflugers Archiv : European journal of physiology - 1 Jul 2010
Steinlein Ortrud K, Bertrand Daniel
Abstract excerpt
Characterized by sudden episodes called seizures, epilepsy was recognized long ago as a neurological disorder that can have multiple forms ranging from benign to life threatening depending upon its severity. Although several evidences indicated that genes play an important role in at least half of the patients, it is only with the advances in molecular biology and genetics that the puzzle about oligogenic and...
Topics
- Animals
- Channelopathies
- Epilepsy
- Humans
- Intellectual Disability
- Mutation
- Neurons
- Receptors, Nicotinic
- Seizures