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Article

Antiphospholipid antibodies impact the protein C (PC) pathway behavior.

American journal of hematology - 1 Oct 2002

Gennari Laura C, Blanco Alicia N, Alberto María Fabiana, Grosso Silvia H, Peirano Andrea A, Lazzari Maria A

Abstract excerpt

Antiphospholipid antibodies may interfere with the PC pathway, displaying a resistance to the activated PC (resistant phenotype). This effect was evaluated by the APCR and the ProCG systems in 36 lupus anticoagulant samples, yielding abnormal results in 47% of APCR(original), 17% of APCR(modified), and 22% of ProCG test. ProCG values correlated with APCR(original) but not with APCR(modified). Most of lupus...

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Share to Activated Protein C Resistance
Share to Antibodies, Antiphospholipid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Reagent Kits, Diagnostic

Source

Identifiers

PMID: 12353314
DOI: 10.1002/ajh.10180

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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