Article
A gene encoding a sphingolipid biosynthesis enzyme determines the sensitivity of Saccharomyces cerevisiae to an antifungal plant defensin from dahlia (Dahlia merckii).
Proceedings of the National Academy of Sciences of the United States of America - 15 Aug 2000
Thevissen K, Cammue B P, Lemaire K, Winderickx J, Dickson R C, Lester R L, Ferket K K, Van Even F, Parret A H, Broekaert W F
Abstract excerpt
We have previously identified a Saccharomyces cerevisiae mutant that is markedly more resistant than wild-type to Dahlia merckii antimicrobial peptide 1 (DmAMP1), an antifungal plant defensin isolated from seeds of dahlia (Dahlia merckii). A complementation approach was followed that consisted of the introduction of a genomic library of DmAMP1-sensitive wild-type yeast into the DmAMP1-resistant yeast mutant and...
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