Article
Deletion of the putative stretch-activated ion channel Mid1 is hypervirulent in Aspergillus fumigatus.
Fungal genetics and biology : FG & B - 1 Jan 2014
Jiang Hechun, Shen Yongnian, Liu Weida, Lu Ling
Abstract excerpt
Calcium ion is a universal and physiologically important molecule affecting almost every cellular function, while Mid1 (mating induced death) is a stretch-activated ion channel localized in the plasma membrane, which can replenish the fungus with extracellular calcium. Aspergillus fumigatus is one of the most important fungal pathogens but little is known about its calcium channels in the plasma membrane. In this...
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