Article
A chimeric ribozyme in clostridium difficile combines features of group I introns and insertion elements.
Molecular microbiology - 1 Jun 2000
Braun V, Mehlig M, Moos M, Rupnik M, Kalt B, Mahony D E, von Eichel-Streiber C
Abstract excerpt
CdlSt1, a DNA insertion of 1975 bp, was identified within tcdA-C34, the enterotoxin gene of the Clostridium difficile isolate C34. Located in the catalytic domain A1-C34, Cd/St1 combines features of two genetic elements. Within the first 434 nt structures characteristic for group I introns were found; encoding the two transposase-like proteins tlpA and tlpB nucleotides 435-1975 represent the remainder of a...
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