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Article

Chloramphenicol resistance in Clostridium difficile is encoded on Tn4453 transposons that are closely related to Tn4451 from Clostridium perfringens.

Antimicrobial agents and chemotherapy - 1 Jul 1998

Lyras D, Storie C, Huggins A S, Crellin P K, Bannam T L, Rood J I

Abstract excerpt

The chloramphenicol resistance gene catD from Clostridium difficile was shown to be encoded on the transposons Tn4453a and Tn4453b, which were structurally and functionally related to Tn4451 from Clostridium perfringens. Tn4453a and Tn4453b excised precisely from recombinant plasmids, generating a circular form, as is the case for Tn4451. Evidence that this process is mediated by Tn4453-encoded tnpX genes was...

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Identifiers

PMID: 9660983
DOI: 10.1128/AAC.42.7.1563
PMCID: PMC105645

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